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Cartilage Regeneration

Specialist procedures to repair and restore damaged knee cartilage

Repairing and restoring damaged cartilage

Once injured, articular cartilage has limited ability to repair itself. This can lead to problems with pain, swelling, feelings of giving way & (occasionally) problems with moving your knee.

There are a number of different ways in which you can treat these problems. Paul has been involved in the creation of ‘cartilage centres’ around the UK where you can be offered the ‘gold standard’ treatment, something only about 10 centres in the UK can offer.

Illustration of a knee joint with damage highlighted across the joint surfaces

Cartilage damage does not heal reliably on its own. Left untreated, defects can worsen and lead to early-onset arthritis. Mr Paul Jermin performs many cartilage regenerative procedures each year and has been involved at national level in commissioning policies for osteochondral allografts and focal knee resurfacing. He also chairs a monthly national complex cartilage meeting drawing specialists from across the UK.

Procedures available include:

  • ACI / MACI – cell-based techniques that grow new cartilage tissue. These are considered the gold standard for treating cartilage defects above a certain size. Oswestry has one of the largest series of people treated with this method in the world and the team are world leaders in research in this field.
  • Osteochondral allograft transplantation – transplants healthy cartilage and bone from a donor to replace a larger defect. Again, this is considered ‘gold standard’ for treating cartilage problems that involve the underlying bone. Paul was involved in the national commissioning document that allowed us to perform these in the UK.
  • Cartiheal – Paul is the first person in the UK to perform this novel procedure involving insertion of a coral based plug. The early evidence for this is excellent but we are still looking to increase our understanding of this novel procedure.
  • Focal knee resurfacing – replaces a localised area with a metal implant

The right approach depends on the size, location, and cause of the damage, alongside your age, activity level, and goals.

  • All regenerative techniques offered (transplant, resurfacing, ACI/MACI etc)

Is this treatment for you?

  • Pain in the knee
  • Swelling that returns after activity
  • Catching or locking from a loose fragment
  • A known cartilage defect found on a scan (only diagnosable from an MRI scan)
  • Pain following a previous knee injury
  • Being under 50 with localised joint damage

Your Journey

Initial consultation

Mr Jermin will assess your symptoms and examine your knee, and review any imaging showing the extent and location of the damage.

Imaging and assessment

An MRI maps the size, depth, and position of the defect. This determines which regenerative techniques are suitable. He will likely take an X-ray that looks at the overall shape of your leg (called a long limb alignment film).

Treatment planning

Mr Jermin will explain the options – from leaving it be through to allograft transplantation or cell-based techniques – and which best suits your defect, age, and activity level.

Surgery

The procedure is carried out at RJAH Oswestry (NHS) or Spire Yale Hospital, Wrexham (private). Some cell-based techniques are staged across two operations.

Recovery and rehabilitation

New cartilage takes time to mature. A carefully staged rehabilitation programme protects the repair while restoring movement and strength.

Mr Jermin

130

knee replacements per year

200

knee arthroscopies per year

30

ligament reconstructions per year

25

osteotomies per year

25

cartilage procedures per year

3

injection treatments offered

15

years of specialist knee experience

2

consultant hospital posts

Hospitals

Entrance to Spire Yale Hospital, Wrexham, with flower beds by the door

Spire Yale Hospital, Wrexham

Entrance sign at the Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry

Robert Jones and Agnes Hunt Orthopaedic Hospital

Cartilage damage rarely improves on its own

Get specialist assessment from a surgeon who leads national cartilage work
Mr Jermin offers consultations at RJAH Oswestry and Spire Yale Hospital, Wrexham